"If you wish to create a brain in 50 MB of code, you must first implement the universe"?
"If you wish to create a brain in 50 MB of code, you must first implement the universe"?
It is, of course, conceivable that the brain contains some kind of computational processes that can be implemented/emulated much more quickly on a biochemical substrate than in doped semiconductors — some kind of quantum computation or something. However, all the evidence we have at the moment points in the opposite direction, and there's no particular reason to believe that the universe is designed to give biochemical systems such an advantage.
The CPU may be physical, but software on it runs on the abstraction which is the CPU's instruction set. The underlying physical nature of the processor is irrelevant.
He was talking about having one machine emulate another - I was pointing out that that means your i7 emulating all of physics.