Humans are squandering antibiotics for the most inane uses, rapidly growing superbugs and resistance along the way. This will become a major public health crisis if nothing is done about it sooner than later.
(I say "previous" - there's an ongoing pandemic of HIV/aids, albeit a more gradual affair, but that's happening to Other People (TM))
We can outsmart them. We have biochemistry and flocks of 30 year old PhD students. They have a random number generator.
The market is failing on this.