I think my example would still apply?

You are better off opting the expensive coffee with the alternative options for lactose intolerant people (soy milk etc.) when compared to buying milk from the road-side stalls (right?)

I have been having coffee almost daily for the past three years and I see a significant improvement in my bones and joints. I can feel it and pointed out by the doctor. Note, I take the coffee with whole milk and not the half-and-half or other kind.

So I would guess it does affect in the long run? Personally it did for me. Not sure at a Macro level.