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Not that I wouldn't like to be as optimistic, too, but Nature does seem to have made enough use of unreliably folding proteins to have come up with BSE, Parkinson's disease, and some others <http://en.wikipedia.org/wiki/Protein_folding#Incorrect_prote... >.

I'm a big fan of Scott Aaronson, too, btw :-) Here's a pic of him demoing the soap bubbles experiment he refers to in that paper you linked to <http://www.scottaaronson.com/soapbubble.jpg >.

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I thought of mentioning that, actually, but figured it would be extraneous. However, if they are all indeed pathological then perhaps we can do our simulated humans a favor and not simulate the pathological path.

Still, as discussed in another comment I made, I seriously, seriously doubt that we will ever simulate any sort of intelligence by raw physical simulation. It just isn't feasible with any realistic computational technique.

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