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I wouldn't sweat it. I think I had almost no karma when we applied.

I don't think it hurts you as much as it can possibly help you. If you have lots of intelligent comments, it's one more reason to put you in the "interview" pile. I think only a few people in our round had notable HN records.

It doesn't sound like they scour your comment history, just if pg recognizes you from an intelligent hn conversation or two it can only help you.

I think quality trumps quantity. I would think if a user posted tonnes of sub-average comments, it may hurt him. And if a user posted a dozen comments of value, it could be a plus.