Researchers have learned to create custom versions of cellular proteins

If you want to build novel proteins from the other direction - based on linking emeperically validated biological functions rather than trying to calculate function from biochemical principles, check out our system at Serotiny [1]. We're taking a bit of a different approach to protein design - build new proteins by reusing biological components with known functions. And though we help design proteins with new functions, these guys design particular enzymatic pockets or predict particular structures - that's amazing.

The Baker lab and all of their colleagues have put so much effort into this goal - I'm eager to see what comes next.

[1] https://serotiny.bio/notes/pinecone/

If anyone is interested in learning more about the Rosetta project, here is a link https://boinc.bakerlab.org/

“Now, it looks as if he and his colleagues have cracked it. Thanks in part to crowdsourced computers and smartphones belonging to over a million volunteers, the scientists have figured out how to choose the building blocks required to create a protein that will take on the shape they want.”

Here's a cool video which gives an overview of the problem and some solution approaches for anyone interested in the general topic.