For a build system similar to Tup, check out http://physics.oregonstate.edu/~roundyd/fac/introducing-fac....
Explicitly inspired by the former, same build paradigm, doesn't use FUSE. Has some neat git integrations. Doesn't work on macOS/Windows yet though.
One funny feature that falls from the design is that you can just keep running & failing a fac build, and it'll nudge you toward the correct build.