It’s been repeatedly demonstrated that yes, it is.
Meaning you have consulted a sea of research that has compared the risk posed by password managers to keeping a mental catalogue of long, not-random-but-pretty-good character strings, using 2fa, and exercising proper security habits?
I don't think you could ever come to an objective conclusion, since the 99%-user doesn't have a near-autistic obsession with security like most of us.
My mom, who is as far removed from tech as you can get, understands why not sharing passwords might be a good idea when one can get hacked and set of a domino effect.
And your comparison is a straw man, the real comparison is trying to remember 50 random passwords to using a password manager because there is a sea of research showing that good passwords should be truly high entropy and random.
Using a password manager doesn’t stop you from using 2fa like your comparison is worded to imply.