Not for some of us just starting our companies. "Worst" case scenario is smaller players that would otherwise play globally will now not play in the EU market.
I was told the other day, "don't worry about it if you don't have sensitive data." That misunderstands risk management. I have plenty of customer potential on this side of the pond, why even risk it until I am large and have saturated my pool? I plan on handling my data completely within the spirit of that law, I just don't want to risk it. Seems on risk alone, others will have to make the same decision as me. We're not losing out really (we can only grow so fast) but those in the EU that might want access to the global market, big or small, might be.