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Node and its ecology of libraries are asynchronous from the ground up. With Twisted or EventMachine, you'll eventually call a library that performs blocking I/O (probably sooner than later) and that will be your bottleneck.

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With Twisted at least there are usually asynchronous versions of commonly needed libraries. Given that, it sounds like they're probably fairly analogous then, right? I assume Node will have the same problem the moment someone grabs a package that's meant for a Javascript framework that isn't explicitly asynchronous.

That is correct.

There aren't really Javascript frameworks that aren't explicitly asynchronous.

- The browser-based APIs are all asynchronous

- The other serverside JavaScript libraries will rely on blocking APIs that aren't supported in Node.JS, so they won't work.

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