Who can say? We can say. We have to decide what's worth our time and what's not. We pass judgment on other people's work. We'll be wrong much of the time, but turning off our critical faculty altogether is worse than being wrong. At least "too much time on his hands" is a statement that can become the basis for a conversation, if you give the speaker some credit instead of assuming his statement is a "substitute for thought." The speaker might be prepared to expand on his opinion if someone wants to hear it. Anyway, a person who sees no value in something is irrelevant to its future. Its future depends on people who do see value in it, not on the open-mindedness or delicate consideration of people who don't.
Furthermore, it's hypocritical for an editor of an extremely popular, carefully polished and curated blog to pretend he doesn't discriminate. People visit Boing Boing because Boing Boing consistently delivers quick nuggets of feel-good eccentricity whose substance is optional to the experience. Like any successful blog, it has a consistent and narrow culture. You won't find an impassioned screed advocating Communist government on Boing Boing, or a gallery of tattoos commemorating murders committed by the tattooees, or Buffy incest fanfic, or a patent for a WiMax antenna, or a discussion of why it's a bad deal for individual investors to buy corn futures.
"The genuinely disruptive, novel artefacts are by definition unpredictable," he says. But he chooses items for Boing Boing that have a predictable flavor. That's okay. The world needs to be organized, and sometimes it has to be organized by collective or individual taste.
Maybe the whole thing is just a plea to protect the fragile ego of creators. Express your taste, guys, but do so in the politest terms possible. Bullshit. If you can't handle a simple "too much time on his hands" comment, then you shouldn't present your work for public consumption. Hide it away from the sight of anybody who might accidentally have an opinion about it. Especially if you're bothered by opinions that (per Doctorow's assumption) are vacuous, because as H.L. Mencken said, injustice is relatively easy to bear; what stings is justice. If you can't handle thoughtless, vacuous criticism, then god forbid anybody takes your work seriously; you'll have an aneurysm.