Ask HN: How do I get my software to stop being flagged by anti-virus vendors?

Our .NET desktop application has been detected off and on by anti-virus software as a false positive for over a year now. It is not obfuscated or packed in any way. Nothing in the binary does anything that could be construed as malicious, I think. The binary is digitally signed by my company's EV code signing certificate. It's detected as Generic/MSIL. I have tried contacting the vendors several times through their report false positives system, and have never gotten a reply.

I'm losing clients because of this. I'm really at a loss here. Hopefully someone here can help. Any help would be appreciated.

Edit: Here's a link to a virustotal scan:

https://www.virustotal.com/#/file/f4550f0c64925bca64c3759a6e279f3a5ecf88fb29d281d2b1103c6c6f5a6320/details