We all know exercise is your best shot at having a healthy heart, a strong immune system, and maybe even a 100th birthday party.
Wasn't this just recently proved false (here on HN)? The sentence may as well read "We all know the sun orbits the Earth" or "We all know that you have to write real programs in C".
Or rather, if you spend most of your day sitting behind a computer, then it doesn't matter how much you exercise, you'll likely be dead by eighty. (Which is quite a liberating viewpoint if you simply accept it.)