Today, Mac usage is declining. The cost:value isn't there and they don't manufacture any high-end kit. Given how much PC you can buy for the same price as a MacBook, like a 32- or 64-core Threadripper or EPYC with a massive GPU which blows any available Apple hardware away, it's not hard to see why. For computational biology, running Linux on it gives you a much more capable and productive system, and even Windows 10 with the Linux subsystem is perfectly adequate. Apple's mistake has been to focus upon only profitable consumer product lines, and drop the ball entirely on the high end. They didn't sell as many high-end units, but they were the driver for Mac adoption in many places, and without that Mac usage will continue to decline. A mediocre laptop isn't good for a lot of scientific uses.