Circulation is not a trash journal, but one of the most important publications in Cardiology. It's surpassed in impact factor only by JACC: http://www.scimagojr.com/journalrank.php?category=2705
"Conflict of Interest Disclosures: Dr. van Dam received a research grant from the Nestec Company. No potential conflicts of interest relevant to this article were reported." Guys, Nestec own the world's biggest coffee machine company, Nespresso.