I've gotten into the habit of organizing my feeds into two groups. People who post infrequently with high quality articles get put into one group. Sites that generate loads of articles (NPR, Guardian, HN) go into the other.

I generally read everything in group one. In group two, I start the day by just marking the entire group read. If something neat comes into group two during the day I might read it when I have a spare moment. Otherwise, it gets flushed.