I would say they are polar opposites. Blockchains are incredibly inefficient since every node has to redo the computations. Adding more nodes does not scale them which is what i consider a core part of scalable systems.
Hi, traditional "blockchains" have full replication which of course doesn't scale as you mention. Replication factor of 5000 is overkill (basically what Bitcoin has). Full replication isn't a prerequisite to building something useful. Instead, replicate less, use the extra nodes to store other shards of data, and make sure you have the right guarantees. That's the path.