I'm using ClojureScript. I would definitely argue that ClojureScript is the right language you should pick up. It's based on JavaScript ecosystem and all pieces from npm are available. It's the largest ecosystem currently. If you argue JVM is the largest one, then just choose Clojure.

For ClojureScript, what package manager? npm. Also you may need Clojars and Maven for some Clojure(Script) packages. But you can use shadow-cljs to abstract the Clojars part. What framework? search in Node.js community, you can use it in ClojureScript. Which database? check out Node.js community. How to run on VPS? it's Node.js question.