I think it depends on the task at hand, whether you are jumping around or focused on a long piece; exploring or debugging ...

Anyway, not everything takes place in the editor.

"The acme user interface for programmers" (http://acme.cat-v.org/) is a good inspiration. It focuses on mouse usage and shows how most systems are as nicely integrated as they could be.

I have hacked together a setup that mimicks acme using a tiling wm, vim (and its amazing remote features), a plumber and a terminal that can send the current selection to the plumber. This way I use vim as I like but I can send it some path:line:col from anywhere with a right click.