Humans likely hunted several species to death after reaching North America, including:

- North American horses (several species)

- North American camels

- Giant Bison

- Tapirs (several North American species)

- Llama's (several North American species)

- Stag Moose

- Gomphotheres (several species, similar to elephants)

Several other species of North American megafauna, such as North American lions and giant beavers likely went extinct due to human activities even though there's no evidence they were hunted directly. e.g. The extinction of most of their prey likely did the lions in.

It's actually quite shocking what humans with rocks, sticks, and empty bellies were able to do. There can be little doubt that the domestication of animals for food has spared countless other species from a similar fate over the last ten thousand years.