Are there any websites where it doesn't work? Looks like in the comments on Amazon this doesn't work for LastPass. I was looking at getting it instead of a Yubikey. I got their bluetooth/nfc key that Google recommends, but I don't have a bluetooth card on my desktop.
It has worked flawlessly everywhere I have tried it (github, Google, Facebook, Dropbox, Fastmail). I don't use lastpass so don't know about that.
Not very helpful, I know..
Lastpass says on their FAQ that they wont support Fido U2f until all major browsers do, but that is on them not the key manufacture.