It's funny that you say that, because it seems that psychedelics may work for a variety of things because they address some lower-level factor, rather than just treating higher-level symptoms.
"In 6-month follow-up interviews, participants were asked: ‘Did this treatment work for you, and if so how?’ and responses were analysed for consistent themes (Watts et al. 2017). Of the 17 patients who endorsed the treatment’s effectiveness, all made reference to one particular mediating factor: a renewed sense of connection or connectedness. This factor was found to have three distinguishable aspects: connection to (1) self, (2) others and (3) the world in general (Watts et al. 2017)."
"In brief, we have proposed that brain serotonin 2A receptor signalling mediates a state of rapid plasticity that is conducive to major change (e.g. in outlook and/or behaviour)—when such change feels necessary (e.g. to aid mental or physical survival). Such a function may be related to humans’ unique capacity for adaptability."
Source/further reading: https://www.ncbi.nlm.nih.gov/pubmed/28795211