For a recent macOS version, do:
0) Make sure you have a recent Xcode installed
1) Install the libsdl2 and libsdl2_ttf frameworks under /Library/Frameworks
libsdl2: https://www.libsdl.org/release/SDL2-2.0.6.dmg
sdl2+ttf: https://www.libsdl.org/projects/SDL_ttf/release/SDL2_ttf-2.0.14.dmg
2) git clone https://github.com/vygr/ChrysaLisp.git ChrysaLisp3) cd ChrysaLisp
4) make (takes about 2s!!)
5) ./run.sh (shows full working gui. Amazing!)