No, because the weight is the cargo. As more and more semi-truck trailer beds transition to aluminum floor joists, for weight reduction, it's an overall increase in productivity because the truck can now haul more cargo weight.
That's possible too, but would be tremendously less efficient as you'd have the same air resistence (or at least a substantial amount) but without the same cargo capacity.
Railroads tend not to develop potholes.
Also, remember that roads aren't made out of head-hardened solid steel - if they were, they'd probably nearly forever.
Rail itself may not get quickly damaged (though they do) however rail wheels, which are made of relatively softer metal, develop all kinds of damage, require the machining away of the damaged surface periodically (as in, wheels shrink over time as mateiral is cut off it to get to new metal below) and only last a matter of years for heavy haul environments: http://www.asa.transport.nsw.gov.au/sites/default/files/asa/...
Search for spalling, shelling and rolling contact fatigue as examples.
(There might be a paper in figuring out the sweet spot given hypothetical costs ...)