When people I'm close with start taking them, they are less interested in being intimate and stop "loving"/being affectionate.
In my experience, having a schedule, exercising and making sure you are around other people help a lot more while preserving your personality.
Have the blues? Cut the fast-digesting carbs and experience less blood sugar fluctuation.
Have bipolar depression that flips into florid mania after a day-long hike? Hoo boy.
I still wanted to be close to people while I was depressed - I just felt useless and unable to do much else. On the SSRI I lost the desire to be affectionate, both around others and when I was by myself. It took around 6-9 months after I came off the SSRI for me to feel like I returned back to a normal state.