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Can it block other extensions?

As noted by someone else in the issue discussion, the old version (works until Firefox 57 arrives) can, but the new webext version can not: https://github.com/gorhill/uBlock/wiki/Firefox-WebExtensions...

WebEx seems like a worse and worse idea (or perhaps it's just the execution) every single time I read anything about it.

IMHO sandboxing extensions is overall a good thing. A rouge extension could have access to e.g. your password manager otherwise.

There's a difference between compartmentalization and limiting your platform's extensibility.

Thing is: I trust uBlock Origin more than I trust Mozilla.