Financially, yes... But... the second part is mostly just the dread of it. I've moved (with family) 6 times in the last 7 years... most of which do to bad luck of contracts falling through in the companies i worked for and them just not having enough work to support the staff... lay offs... and while its disruptive, there is actually a ton of growth out of it that, honestly, has been worth it... Just because something is hard up front doesn't at all make it a bad choice...
Yeah. The inability to move is actually a huge friction to life and the economy. People are not able to go to where the jobs (or where they can afford a comfortable life) and companies aren't able to get the people they need.
We should seriously have a discussion about government-subsidized moves.