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Also be aware that iOS 11 seems to be incompatible with Windows Server 2016. Seems to be an http2 implementation problem.

Seems to be Mail.app if it's a fault on Apple's side. I wonder if the Outlook.app works correctly?

In what way? That seems like an extremely serious problem, given how many LOB apps run on Windows Server.

I don't have much details.

Where I work we received an email urging us not to upgrade, I believe for that reason.