Munich/Bayern - old school, conservative, traditional.
Berlin - multicultural, hipster.
Kind of like SF vs. Dallas.
That said, they are both very German and it's a little bit of a stretch to say they are different markets.
But Germany and Spain are night and day different and building for EU-wide is very hard.
Not only are there different markets, but Europeans have strong cultures, which include behaviours - they don't jump a 'the new thing' because it's cool.
America is a land of fads and trends, people like new activities, new dynamics - also, people are always in search of identity, and 'brand power' is powerful in the US across the board, just as some American brands have considerable cultural power in China.
There are basically no places in Europe with a critical mass of early adopters for anything in tech, so it's tough. Some spots, yes, and numbers overall, yes. But no hot-zones.