If you actually look at the routes [1] (as linked by another user [2]) the Glasgow-Liverpool makes some of the most sense. The UK has long term problems with its north-south divide, putting a hyperloop into London and the south will be crazy expensive and meet tons of opposition. Linking the northern cities will be brilliant infrastructure and form a solid backbone for future economic development. Eventual extension to London is also possible with less opposition.

We need to unite Britain, and a northern hyperloop could go a long way to doing that.

[1] https://arstechnica.com/cars/2017/09/hyperloop-one-colorado-... [2] https://news.ycombinator.com/item?id=15250816