Mixing up my p's and q's, and my b's and d's were a big problem when I was young but I luckily grew out of that since they were considering putting me into remedial education because of it.
I also find I've developed a lot of my own pneumonics. So for > and < I know that the converging side is narrow and therefore it is the lesser side, the divering side is broad and as such is the greater side. Or as someone from the west coast of an island - I figure out east and west by imaging my country knowing that I'm on the west coast.
Funnily enough north/south or up/down don't cause me trouble. It's only things that have vertical symmetry or that can rotate that confuse me.