IBM pitched Watson as a revolution in cancer care, but it’s nowhere close
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The MD Anderson situation was a debacle of monumental proportions. Such claims on cancer care are quite unethical in my view given that it gave a lot of very sick people false hopes and diverted a lot of hospital attention and funding away from stuff that actually works.
My sentiment of IBM these days is they sell software which is purposely made bad...and people buy it because, well no one ever got fired for going with IBM.
> “It’s fine,” Dr. Sujal Shah, a medical oncologist, said of Watson’s treatment suggestion while discussing the case with colleagues.
> He said later that the background information Watson provided, including medical journal articles, was helpful, giving him more confidence that using a specific chemotherapy was a sound idea. But the system did not directly help him make that decision, nor did it tell him anything he didn’t already know.
I don't know, that doesn't sound bad at all. Perhaps it's just a case of overhyping. But if a computer can do recommend the same treatment as an expensive oncologist with years of training that's actually pretty good!
On the other hand it is quite baffling why doesn't FDA require a clinical trial or any independent review of its capabilities before allowing its use in clinic. It's a bit like Boeing certifying its own planes, I guess.
Because it's a tool for informing doctors, not a medical treatment. We don't have a clinical trial before PubMed rolls out a new search form either.
BTW I've worked with regulated software and it's not pretty. Just to update the firmware you have to fill out a ton of paperwork (because somebody died once after a firmware update and the firmware update was found to be the root cause). Regulation and review doesn't really make things tremendously safer, it just provides an audit chain so you can point at something when it does go pear-shape
Laws are changing to include "software medical devices" in health regulation. The FDA recently recognized this as a gap.
This isn't quite correct - FDA has always regulated software medical devices. It is true however that the FDA is looking a lot closer at software than they did in previous decades, and is releasing guidance (e.g. recently on cybersecurity) that signals intentions moving forward. They definitely have signaled that they don't believe they were focused enough on software.It's important understand that FDA approval to market is always done in terms of indications for use. You don't approve a device full stop, you approve it (and evaluate it) in terms of the indications. Only in this context can you determine if you have a 510k path (i.e. short cut) or need a PMA (i.e. clinical trial). It is also important to realize that different panels in the FDA (i.e. the type of device you are making) have different evaluation criteria.
So "Watson" is unlikely to ever be cleared per se (it is a tech platform) but you are likely to see individual Watson enabled systems file 510ks for particular indications. If I recall correctly this has already happened.
While I get the impression FDA and industry prefer 510ks as much as possible, personally I don't see how this is close enough to anything out there right now for that to pass the smell test.
My guess would be that some `Watson` equivalent stuff will be 510k'd in as part of an MRI, CT or DBT imaging system or a CAD tool working on these systems. I think it'd take a while though, I don't think the regulatory science is there yet for actually showing value.
There have been approved CAD systems separate from imaging systems since the 90s.
"Value" is a nebulous term. FDA looks specifically for "safety & efficacy", and the criterion for each are rather dependent on the intended use.
Sigh. Let's remember that in medicine (a severely resource-constrained system), costs operate in a zero-sum environment. $200-$1,000 spent on Watson is $200-$1,000 not spent on some other treatment or human labor. And, in our current environment, specialist doctors will always have to re-do the diagnosis suggested by Watson, because guess who is held legally responsible, in the case of a malpractice suit? Not IBM, but the doctor co-signing the "recommendation".
Looks to me like a giant pattern recognition system. The best assessment I found in the article:
> He said later that the background information Watson provided, including medical journal articles, was helpful, giving him more confidence that using a specific chemotherapy was a sound idea. But the system did not directly help him make that decision, nor did it tell him anything he didn’t already know.
Pretty much all attempts at AI are pattern recognition systems. I think the AI hype will die down a bit, after we see more of the high profile AI programs underdelivering on marketing's promises. But we'll get some gems that do deliver something useful.
I just guess IBM bit off more than they can chew on this one. It's an old, slow, uninnovative company, trying to do what the cool kids are doing by putting all of their money on it.
All attempts in modern AI. Most interesting research from the 60s and 80s wasn't based on pattern recognition.
Pattern recognition is a fundamental component of intelligence, but not all attempts at AI are based on supervised learning (ie "simple" pattern recognition).
Source: years of working in Energy/Commodity trading systems market and seeing several botched big 4 implementations that vendor/boutique shops can do at 1/10th the price.
And that confidence is what moves the project forward, until the customer sees dates slipping, at which point it's too late.
You're not buying thousands consulting hours and some big data services... you're buying Watson
0: https://www-01.ibm.com/software/passportadvantage/pvu_licens...
This is why Watson is a disappointment and every Watson project ends in cost overruns and failure.
(I guess companies like Flatiron Health are working in that direction.)
In the area of cancer treatment, my guess is that the reason specialists are highly paid/trained is because the analysis and judgement required is highly manual and varied. Surgical intervention, prescription medications, targeted radiation treatment machines, patient psychology and counseling. Other than maybe guessing the prescription based on symptom list, what could the AI profitably help with?
Perhaps more likely, human doctors are actually quite good and AI has yet to out do them.
> He said later that the background information Watson provided, including medical journal articles, was helpful, giving him more confidence that using a specific chemotherapy was a sound idea. But the system did not directly help him make that decision, nor did it tell him anything he didn’t already know.
This type of thinking is reason true ML adoption is still sparse. Analytics should be viewed as a supplement to decision making, not a replacement.
Manipulative marketing tactics by IBM and others are largely to blame. I'm confident that over time, as the general population becomes better educated on the topic, the perspective will shift.
Wow the way they describe Watson is just like a massive book of documentation, with some NLP functionality layered on top to interface with the doctors. Keeping the database up to date must be a huge undertaking. Also this:
> "Given the same clinical scenario, doctors can — and often do — disagree about the best course of action, whether to recommend surgery or chemotherapy, or another treatment. Those discrepancies are especially wide for second- and third-line treatments given after an initial therapy fails, where evidence of benefits is slimmer and consensus more elusive."
Having an expert doctors opinion hard coded into the machine sounds good, but it won't be as good as a doctor in the room who can pick up on all sorts of other cues that I'm not sure how'd you even type into a computer. Things like breathing patterns, reaction to tactile stimuli, fuzzy logic ('that hurts, that hurts more'), facial expressions and so on.
Seems like this project has a long way to go, to get to the standard the IBM marketing team are pretending it's already at.
Isn't this a good thing then that there's a digital assistant to ensure doctors are up-to-date and provide the right treatment plans?
but on the other hand, IBM's negotiation with MD anderson was one kind of a deal - instead of paying for hospital data, IBM made hospital pay...
And it's intentional! They have a strategy of inventing new words that sound all scientific (like 'cognitive computing') but there is absolute no meaningfull research from them. Its like the whole company has become a parody.
Any companies that allows their employees to talk to IBM has the problem that afterwards their employees understand less of actual problem domain -- and the knowledge they think they gained from that interaction .. its all 'IBM and consultancy buzzwords' rather than the industry-standard terminology fueled by actual research and science.
http://www.underconsideration.com/brandnew/archives/new_logo...