Everything from support, to sales, to web development, admin, security, etc.
I'd list all the telecommuting job sites, but there seems to be a thousand of them now.
The US median income is about $37,000 per year ($17-$18 per hour). To get beyond ~$13 to ~$17 per hour doing lower skill telecommuting work, you have to have a resume with something meaningful on it.
If you're from Appalachia, it's not difficult to teach yourself any number of skills (from database admin to javascript), go to a local small college to pad your resume with that, get a certification or two if applicable, and then get a job working remote at an entry level tech job that pays considerably better than anything local (few of those jobs exist locally there). A person can go work at a local AT&T or similar store doing sales in an Appalachian town, get some sales experience, and then go apply for a remote sales job making more than they'll get locally. Particularly right now is an ideal time, the US labor market is getting very tight.
I grew up in Appalachia and entirely self-taught my way out of it in the mid 1990s. It was a helluva lot more difficult to do back then. And that process is trivial compared to working in a coal mine, and it's a lot less soul destroying than toiling away for a decade earning $10-$15 at a local Walmart.