FWIW, I do find Interface to be subjectively noticeably more pleasant than Roboto in the comparison here.
The most informed comparision can be made when the x-height is optically equivalent. The other option, cap height, isn't as useful because it is then harder to judge the lowercase (a majority of the letterforms).
Sure, you shouldn't be designing an interface with those sizes, but it may be something to consider for some zooming interfaces (primarily maps with lots of tags: street names, POIs, etc.)