For example if a barbarian get really high rolls for all stats except strength is it actually a really a good roll for that character or should you consider re-rolling?
Edit: Oops, I completely forgot about the ability to reassign points between stats. Thanks to batiudrami & beloch for pointing that out.
As an interesting side note: An older (A)D&D game series, Eye of the Beholder, allowed you to modify the stats any way you wanted after rolling, which meant you could just set all stats to max if you wished. I've read from somewhere that this was done so players could "import" their pen & paper RPG characters with the correct stats points into the game. Dunno if that's true though.