Could toxic air on planes make frequent flyers ill?

As a frequent flier I've found flying is much more stressful to my body than one might expect. Long flights make me completely miserable, sometimes for multiple days afterward. Plus there is social isolation and a strange sense of detachment from being away from home and friends for so much time. I was in denial flying was that uncomfortable for years (why would sitting in an uncomfortable chair breathing dry air for a few hours leave me THAT uncomfortable?

I'm skeptical of what amount to anecdotal claims about health problems from flying. It's an unexpectedly physically stressful job which I think will tend to make people over attribute health problems to it.

The article does not mention the constant noise in a plane. For me that is also very invasive and feels very unhealthy. I always feel exhausted after a while.

Any time I board a plane I get the distinct sense that the cabin air contains toxins of some kind, as it consistently smells like exhaust air.

I wish they'd have mentioned that jet fuel uses leaded gasoline still. Lead poisoning could explain some of these symptoms.