The lower gravity than Earth bit sounds like the most debilitating thing about Martian colonization. One of the reasons why I think Venus cloud cities would be a better long-term bet for baseline humanity:
Wow, soccer would be epic in low G!
[0] is this a thing?
And, of course, bones are not monolithic atomic objects but complex living things. Different parts of them may be described by either of those two cases, or others.
It sounds terrible to suggest sending your elderly relatives to an old folks home on Mars, though.
I want to know where the fuck are our Earth based cloud cities.
Surly there's a market and it'd be (I'd guess) 3 orders of magnitude easier than Venus.