If you need to close that gap between the performance of multiprocessing, and multithreading, then you probably shouldn't be using Python, or any language of the same shape, in the first place.
There is one other option I'd like to see: multiprocessing style, but with multiple Python interpreter instances in the same process — one per thread. There would still be the hard delineation of data boundaries between instances, but less overhead for pushing data between them.