Not first time, it's stupid how GitHub accepts anything as DMCA request.
If it's possible, then it would be a good act of protest to require individually signed (by an actual person with a pen, not a picture of a signature), individually snail-mailed requests. This would at least make the process take O(n) time and O(n) money, making it a bit harder to abuse.
It's a real question, can they easily challenge some requests and maintain their safe harbor status?
Does your link address that question? Is your opinion on the DMCA well informed?
Modifying uBlock mitigates the argument but doesn't entirely remove it. For example if the people who control uBlock control a third-party source that allows the same preventions to be implemented then technological changes have been made but the situation is legally homologous (AIUI, IANAL).
IMO uBlock need to provide facility for a domain to be blocked but say "search online to find blocklists" and have no legal associations with the blocklist maintainers; akin to how emulator sites manage ROMs, they stay as legal separated from them as possible. Putting Google in the middle makes getting sued harder, in theory Google is linking the people to the tech/info that enables the alleged infringement.
Remember DMCA is strongly weighted towards the accuser in the initial instance and that a service provider has to take down content in order to maintain their safe-harbour protections, leaving it to the alleged infringer to counter the accusation (guilt until claim of innocence).