You can see this demonstrated in their demo where highlighting the text garbles it -- because they render without using browser technologies, they miss out on browser implementations of things like highlighting. (Another example: their "get in touch" link in the demo is not a real link and can't be right-clicked, indexed by search engines, etc.)
In the specific context of a PDF that is perhaps inevitable (PDFs likely need special text layout) but in the larger context of random native apps, you only get a "free" port to the web by cutting out web features.
With that said, let me emphasize again that in the right domains this is all super awesome. It just doesn't solve the problem of making good webapps.