Should one learn ES2015 before learning ES5? Is there any value or need to learn ES5 if you're not maintaining an old codebase?
If supporting IE or out of date mobile devices is worth your time (it might be, it might not be - consider CSS grid won't work, flexbox won't work, webcrypto won't work, HTML5 clipboard won't work, and you'll need double the time to deal with them and their awful devtools) transpiling is a good option.