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Yes.

Fructose loads your liver. Sucrose breaks down into glucose (which can be metabolized by many cells) and fructose (which is only metabolized by the liver). They're both bad when over consumed.

This laid out pretty well in The Obesity Code by Jason Fung (a real doctor).

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As I understand it, it's worse still. While glucose can be directly converted to energy, fructose must first be turned into fat, before it can be converted to glucose or ketones.

This fat will be stored in the liver.

The more fat you have in your intestines the more insuline resistance you'll have. Which in the end will screw with the entire body in various ways.

Fructose is mostly turned into glucose and metabolized that way. No need to turn it first to fat. https://en.m.wikipedia.org/wiki/Fructolysis

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