Don't worry too much, each person is different. I am WFH'ing for a good several years now, and largely enjoy it. Also, I believe, in my case pros outweigh the cons.

Lucky to have a family, which does help a great deal in this situation. But, I do sometimes worry about it, but as a result compensate for it - exercising to stay fit/lean. Also, always try to be on the cutting edge of tech - HN/similar is great for that.

Edit: Just to add two more points:

1) Social networks: One might think, that they will help in this situation. But again, its different for everyone. I find, in my case their use is detrimental. So after having disconnected from them totally (save a pseudonymous twitter a/c for news/venting), I find it more peaceful, also I found my friendship with good friends has improved. And Facebook friends withered off.

2) Another thing, I learnt a few years ago, some people need social interactions to re-energize where as for some people it is solitude. Are you the type, who if goes for a walk in the park, and when people try to hold a long conversation, do you like it? Or would you rather be left alone after greeting/short-conversations. I definitely, am the second type. (If I am portraying my personality to be totally anti-social, then that's inaccurate. As my social needs are fulfilled well, by family and friends. May be if I had less of that, then would definitely like to have long talks with strangers in the park. Each person has different situation and needs, that's the key point).