There are known and measurable negative social effects that is strongly affecting people with high intelligence as measured by standard tests. Some fraction of highly intelligent people will certainly also be highly socially skilled - as skills really don't appear to be exclusive, a few will have an exceptionally strong drive to succeed, and some fraction will be in the right place at the right time. It is likely that those we know of have some measure of either, of those characteristics, and that the others simply never rose from obscurity however talanted they might have been. There are exceptions, as there is to all generalisations.
It's not always about fitting into broader society. Tesla fit into a small niche of people who were into the same things. That's very similar to Shannon's story.