I usually ignore server side rendering or isomorphic rendering. I'm not saying all projects should ignore it but you're really talking about a high level of optimization if you need it. And if you're reaching that level of optimization you probably shouldn't use Python.

Server side rendering only makes the first view faster. After that, everything is rendered on the client and faster that way. And if you use caching with progressive web apps or just file caching in general, the first view will be fast after. So you're only optimizing for the first of the first. You can then provide the initial data in the page request so that saves a round trip on the first request while still rendering on the frontend.

I say all this to just point out that there are many ways to speed up your frontend without doing SSR and they are much easier to implement with Python. So I'd rather exhaust all these techniques before implementing SSR. If I get to that point though, I suspect Python might be the slowest part of your stack. And lastly if you are doing SSR for SEO purposes then just use a prebuilt prerender service.

With all that said if there was an easier way to SSR with Python/Django, I'd definitely use it. But Jinja on the frontend doesn't sound like that answer.