Iranian-American here ... I think the days where Americans hold anti-Iran sentiments are long past. At least, amongst educated types. There's a lot of curiosity about Iranians and the culture. For example, I just went to the Museum of Fine Arts in Houston, Texas and was surprised to see an exhibit of contemporary Iranian art (i.e., modern art made by young artists recently living in Tehran, NYC, London, etc). The Iranian restaurants, even in Texas, are packed, and half the guests are non-Iranian, American born people.
Probably going through the experience of becoming jaded about our own government helped. We (USA) are now one of those countries where people have to say "don't look at the government, the people are decent." So people here with an ounce of curiosity about the world understand the same as to Iran. And then you have more people who even understand the role the US played in destabilizing Iran which put it on trajectory to its current regime.