As an employee-level programmer, you're generally not going to find meaningful work. You're going to get handed messes, and in exchange for a paycheck you hand back slightly less chaotic messes that do some more stuff.

Switching jobs probably isn't going to fill the frustration you feel. The vast majority of jobs aren't meaningful. The ones that are don't pay particularly well or have other quality of life issues - school teachers aren't well paid, healthcare providers require vast amounts of training and work insane hours, and the overwhelming majority of artists don't make it.

The solution is to have work be the thing you do for forty hours a week that pays for the meaningful things you do in your life. Go home after eight hours. If you have a partner and kids, spend time with them. If you don't, consider getting them. Make some art in your spare time, or build side projects that have meaning for you. Go dancing. Make music. Write a blog. Write angry rants about how your work is meaningless. It really doesn't matter much.

There's no shame in quietly building a happy little life for yourself. You just don't hear about it too often because those folks are out being quietly happy.