Hacker News Reader

Comment by aantix | Hacker News Reader

Exercise. Fasting. Daily Aspirin. Daily Metformin.

Together should put you in a pretty good position.

Also, if you really hate fasting, indications are eating a moderate protein, high fat (isocaloric) ketogenic diet is almost as good without the discomfort. And if you do that you probably don't need the Metformin :)

Been doing IF this entire year (12pm-8pm feeding window). You definitely get used to being hungry in the mornings for a few hours.

This is anecdotal, but I've never felt better! I try to convert everyone :)

Also, there are lots of people that do IF AND keto :)

Daily Aspirin is very harsh on the stomach.

right, but if you are at a high risk for heart attack it is worth the risk.

Ask your doctor how the risk/reward plays out for you. Never take medical any other than ask your doctor from a message board.

Not the low dose version. I've been taking them for 5+ years and never once had a problem with the stomach (that wasn't obviously something else).

Except the increased risk of heart attack and the damage to kidneys and bowels...

Huh? Taking low dose aspirin lowers the risk of heart attack. No indication of kidney issues[0]. Where are you getting your information??

[0] http://www.health.harvard.edu/heart-health/is-low-dose-aspir...

As for the internal bleeding risks.

http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2036.2006....

"These results translate into an absolute rate increase with aspirin above placebo (the incidence of cases of major GI bleeding attributable to low-dose aspirin) of 0.12% per year (95% CI: 0.070.19% per year).[20] Based on this value, 833 patients (95% CI: 5261429 patients) would need to be treated with low-dose aspirin instead of placebo to cause one major GI bleeding episode during a 1-year period (i.e. the NNH is 833)"

Why Aspirin and Metformin?

Small (usually half of normal one) portions of aspirin and metformin are found to extend a lifespan. Although, I'd recommend to take aspirin everyday every second or third month, but that's my preference.

What do you mean by "take aspirin everyday every second or third month"?

Reply on news.ycombinator.com