The amount of complexity I'm willing to accept is proportional to the the difficulty of the problem. In this case it's manipulating web pages, which shouldn't be too hard. This isn't a knock on React in particular, but it seems all the major vendors are competing on complexity. React has "fibers", Ember has a "virtual machine", Angular has their own overblown architecture (I don't know anything about it, and don't want to).
Now that the DOM API is implemented in a standards-compliant way across most browsers, it should be the perfect time to use it. I don't like the current mess that is front-end web development, and more of the status quo isn't going to get any simpler, quite the opposite.
Shameless plug for my own DOM utility: http://simulacra.js.org