"Resveratrol (RSV), a red wine component, and red wine itself exert cardio- and nephroprotective effects by modulating the Nitric Oxide system (NO). Elucidating both upstream and downstream molecular mechanisms of the SIRT-1 pathway is an open field of investigation that can explain its role not only in long-term processes, such as aging, but also in short-term processes, such as protection against ischemic damage." [1]
Water doesn't do that.
If you are talking only about alcohol itself, studies show a link to protecting against heart disease:
"The idea that moderate drinking protects against cardiovascular disease makes sense biologically and scientifically. Moderate amounts of alcohol raise levels of high-density lipoprotein (HDL, or “good” cholesterol), and higher HDL levels are associated with greater protection against heart disease. Moderate alcohol consumption has also been linked with beneficial changes ranging from better sensitivity to insulin to improvements in factors that influence blood clotting, such as tissue type plasminogen activator, fibrinogen, clotting factor VII, and von Willebrand factor. Such changes would tend to prevent the formation of small blood clots that can block arteries in the heart, neck, and brain, the ultimate cause of many heart attacks and the most common kind of stroke." [2].
So let's work in your terms of drinking alcoholic beverages versus water and let's say you knew you were at a high risk of cardiovascular disease - could alcohol help you over water? Yes the science seems to support that.
[1] https://www.ncbi.nlm.nih.gov/pubmed/20932649
[2] https://www.hsph.harvard.edu/nutritionsource/alcohol-full-st...